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Table 4 Sensitivity of 1, 2, 4 and 6 skin snips taken 1, 3 and 5 years after the last ivermectin treatment

From: Modelling Neglected Tropical Diseases diagnostics: the sensitivity of skin snips for Onchocerca volvulus in near elimination and surveillance settings

   Sensitivity (%)a
   Time after last treatment
   1 year 3 years 5 years
0 % reduction in microfilarial production per treatment
  Number of skin snips    
  1 17 42 51
  2 31 67 76
  4 53 89 94
  6 67 96 99
7 % reduction in microfilarial production per treatment
  Number of skin snips    
  1 10 30 38
  2 18 51 62
  4 33 76 85
  6 45 88 94
35 % reduction in microfilarial production per treatment
  Number of skin snips    
  1 0.3 1.5 2.4
  2 0.6 3.0 4.7
  4 1.3 5.8 9.2
  6 1.9 8.6 13.5
  1. aEstimates of sensitivity are based on k m  = 0.42 (mean of the country-specific estimates for 1–10 adult female worms).