Modelling Neglected Tropical Diseases diagnostics: the sensitivity of skin snips for Onchocerca volvulus in near elimination and surveillance settings

Table 4 Sensitivity of 1, 2, 4 and 6 skin snips taken 1, 3 and 5 years after the last ivermectin treatment

		Sensitivity (%)^a
		Time after last treatment
		1 year	3 years	5 years
0 % reduction in microfilarial production per treatment
	Number of skin snips
	1	17	42	51
	2	31	67	76
	4	53	89	94
	6	67	96	99
7 % reduction in microfilarial production per treatment
	Number of skin snips
	1	10	30	38
	2	18	51	62
	4	33	76	85
	6	45	88	94
35 % reduction in microfilarial production per treatment
	Number of skin snips
	1	0.3	1.5	2.4
	2	0.6	3.0	4.7
	4	1.3	5.8	9.2
	6	1.9	8.6	13.5

^aEstimates of sensitivity are based on k _m = 0.42 (mean of the country-specific estimates for 1–10 adult female worms).

ISSN: 1756-3305