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Fig. 1 | Parasites & Vectors

Fig. 1

From: Insulin-like growth factor-I serum levels and their biological effects on Leishmania isolates from different clinical forms of American tegumentary leishmaniasis

Fig. 1

Effect of IGF-I on parasitism in THP-1 with isolates of Leishmania from patients with cutaneous (CL, n = 8), mucosal (ML, n = 7) or disseminated (DL, n = 7) forms of the disease. THP-1 cells infected with the isolates of Leishmania (V.) braziliensis were stimulated or not with IGF-I (50 ng/ml) throughout the culture period of 48 h. Parasitism was evaluated by optical microscopy and the result is represented as the number of parasites per 100 cells (a). Parasite load ratio upon IGF-I-stimuli and basal conditions in THP-1 cells infected with Leishmania (b). Horizontal bar represents the mean value. Results representative of two experiments with each isolate tested in triplicate

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