Fig. 2From: Insulin-like growth factor-I serum levels and their biological effects on Leishmania isolates from different clinical forms of American tegumentary leishmaniasisInfection ratio of THP-1 cells infected with Leishmania isolates from patients with different clinical presentations upon IGF-I stimulus. Infection ratio between parasite load of cells upon IGF-I stimulus and basal infection without stimulus. THP-1 cells were infected with Leishmania isolates from CL (n = 8), ML (n = 7) or DL (n = 7) and maintained in culture with or without IGF-I (50 ng/ml) for 48 h. Parasitism was assessed by optical microscopy and the results expressed as number of amastigotes/100 cellsBack to article page