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Table 3 Mean arithmetic on animal tick counts 12 hours after infestation of dogs with Rhipicephalus sanguineus

From: Comparative efficacy of oral administrated afoxolaner (NexGard™) and fluralaner (Bravecto™) with topically applied permethrin/imidacloprid (Advantix®) against transmission of Ehrlichia canis by infected Rhipicephalus sanguineus ticks to dogs

Day

Arithmetic mean tick counts 12 hours after infestationa

Control

Advantix®

NexGard™

Bravecto™

M

M

F

df

P

M

F

df

P

M

F

df

P

Day 30

35.3

3.5

14.56

3

< 0.0001

24.0

14.56

3

0.0288

22.5

14.56

3

0.0143

Day 35

31.8

0.9

15.15

3

< 0.0001

25.6

15.15

3

0.2202

16.3

15.15

3

0.0036

Day 42

35.5

2.3

16.27

3

< 0.0001

30.1

16.27

3

0.3156

15.5

16.27

3

0.0007

Day 49

34.5

1.5

22.62

3

< 0.0001

33.1

22.62

3

0.7640

24.3

22.62

3

0.0318

Day 56

33.6

1.9

16.01

3

< 0.0001

34.9

16.01

3

0.8187

22.0

16.01

3

0.0402

Day 63

28.5

5.8

5.77

3

0.0003

17.3

5.77

3

0.0507

19.5

5.77

3

0.1136

Day 70

26.6

0.3

24.65

3

< 0.0001

20.1

24.65

3

0.0714

25.1

24.65

3

0.6687

Day 77

24.6

3.9

7.68

3

0.0002

24.0

7.68

3

0.9001

19.0

7.68

3

0.2639

Day 84

31.8

0.3

55.67

3

< 0.0001

36.0

55.67

3

0.1986

22.9

55.67

3

0.5283

  1. Abbreviations: M, arithmetic mean, F, F-statistic, df, degrees of freedom, P, P-value (one-way ANOVA with a treatment effect in comparison with control group)
  2. acounts based on ticks attached to the dogs, excluding ticks in the crates