Comparative efficacy of oral administrated afoxolaner (NexGard™) and fluralaner (Bravecto™) with topically applied permethrin/imidacloprid (Advantix®) against transmission of Ehrlichia canis by infected Rhipicephalus sanguineus ticks to dogs

Table 7 Monitoring of Ehrlichia canis transmission by infected Rhipicephalus sanguineus ticks to dogs

Group	Animal ID	Temp^a	Platelets^b	PCR	IFA
(1) Control	2A7 53C	40.1	199	NEG	NEG
	2AA 200	39.3	114	POS	POS
	4C6 76B	39.9	226	POS	POS
	4C6 FCC	40.5	155	POS	POS
	500 362	38.9	257	POS	POS
	CC1 5A3	40.6	172	POS	POS
	CD0 4 F5	38.8	204	NEG	NEG
	DF7 4DB	39.3	132	POS	POS
(2) Advantix^®	284 012	38.8	392	NEG	NEG
	2AA 66 F	39.5	251	NEG	NEG
	2 AD 36C	40.3	347	NEG	NEG
	4C7 17D	40.6	396	NEG	NEG
	4DD 2E5	40.0	252	NEG	NEG
	4 F4 A1D	39.4	323	NEG	NEG
	B2B 7D0	40.4	13	NEG	NEG
	CD3 EC5	39.6	218	NEG	NEG
(3) NexGard™	289 BB6	40.6	264	NEG	NEG
	2 AC 905	40.5	70	POS	POS
	4DE 28 F	39.9	145	POS	POS
	4EF 726	40.1	27	POS	POS
	B2B 745	39.9	314	NEG	NEG
	CBF E82	39.0	231	POS	POS
	DF7 5C1	39.9	320	NEG	NEG
	E17 7C8	39.3	248	NEG	NEG
(4) Bravecto™	285 8A5	40.1	356	NEG	NEG
	2A8 C98	40.8	103	POS	POS
	4D9 0DB	40.3	134	POS	POS
	4 F7 4B1	39.6	362	NEG	NEG
	5D3 A6A	39.0	225	NEG	NEG
	E16 E41	39.0	227	NEG	NEG
	E17 4A6	39.3	184	NEG	NEG
	E18 950	39.4	202	NEG	NEG

^aMaximum body temperature measured (> 39.4 °C is significant)
^bMinimum platelet counts as a measure for thrombocytopenia (normal range between 200 × 10⁹/l and 500 × 10⁹/l)
Abbreviations: POS, Positive, NEG, Negative

ISSN: 1756-3305