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Fig. 2 | Parasites & Vectors

Fig. 2

From: Immunomodulatory effects of tick saliva on dermal cells exposed to Borrelia burgdorferi, the agent of Lyme disease

Fig. 2

Effect of tick saliva on inflammatory mediator production by THP-1 cells, as measured by antigen-capture ELISA. Supernatants from THP-1 cells grown for 24 h: unstimulated control (control), incubated with B. burgdorferi (MOI 10:1) (+Bb) alone, B. burgdorferi and 64 μg saliva (+Bb + Saliva) or B. burgdorferi and 0.7 μM PC (+Bb + PC). Supernatants were subjected to antigen capture ELISA for IL-6 a, IL-8 b and TNF-α c. Cells exposed to B. burgdorferi plus tick saliva showed a significant decrease in inflammatory mediator production. ***P < 0.001

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Parasites & Vectors

ISSN: 1756-3305

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