Table 3 MSP1, MSP2 genetic diversity, allelic frequency and allelic families fragment sizein mild and severe malaria patients in Gezira State, Sudan (January 2012)
|  | Uncomplicated malaria (n = 90) | Severe malaria (n = 50) |  | ||||
|---|---|---|---|---|---|---|---|
Gene/Allele | Positive n (%) | Fragment size (bp) | No. of alleles | Positive n (%) | Fragment size (bp) | No. of alleles | P-value* |
MSP1 | Â | Â | Â | Â | Â | Â | Â |
 MAD20 | 16 (17.8) | 100–380 | 7 | 3 (6) | 100–300 | 7 |  |
 K1 | 5 (5.6) | 160–300 | 6 | 5 (10) | 180–300 | 4 |  |
 RO33 | 13 (14.4) | 160 | 1 | 3 (6) | 160 | 1 |  |
 MAD20/K1 | 10 (11.1) |  |  | 4 (8) |  |  |  |
 MAD20/RO33 | 14 (15.5) |  |  | 8 (16) |  |  |  |
 K1/RO33 | 9 (10.0) |  |  | 8 (16) |  |  |  |
 MAD20/K1/RO33 | 10 (11.1) |  |  | 6 (12) |  |  |  |
 Total | 77 (85.5) |  | 14 | 37 (74) |  | 12 | 0.326 |
 Total MAD20 | 50 (55.5) |  |  | 21 (42) |  |  | 0.078 |
 Total K1 | 34 (38.0) |  |  | 23 (46) |  |  | 0.343 |
 Total RO33 | 46 (51.0) |  |  | 25 (50) |  |  | 0.724 |
MSP2 | Â | Â | Â | Â | Â | Â | Â |
 FC27 | 20 (22.2) | 200–600 | 10 | 11 (22) | 200–600 | 9 |  |
 IC1/3D7 | 19 (21.1) | 250–700 | 11 | 8 (16) | 350–700 | 11 |  |
 FC27/IC1/3D7 | 49 (54.4) |  |  | 23 (46) |  |  |  |
 Total | 88 (97.7) |  | 21 | 42 (84) |  | 20 | 0.002 |
 Total FC27 | 69 (77.0) |  |  | 34 (68) |  |  | 0.265 |
 Total IC1/3D7 | 68 (76.0) |  |  | 31 (62) |  |  | 0.091 |