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Table 3 On-animal flea counts in naturally infested homes when dogs were administered either fluralaner or afoxolaner oral treatments

From: Evaluation of fluralaner and afoxolaner treatments to control flea populations, reduce pruritus and minimize dermatologic lesions in naturally infested dogs in private residences in west central Florida USA

Treatment group

# dogs at day 0

 

Days post-Treatmenta

   

Day 0

Day 7

Day 14

Day 21

Day 28–30

Day 40–45

Day 54–60

Day 82–86

Fluralanerb

34

Geomeand

28.3

0.3

0.1

0.1

0.0

0.0

0.0

0.0

 

range

(5–155)

(0–6)

(0–3)

(0–2)

(0–0)

(0–1)

(0–0)

(0–0)

 

% controle

 

99.0

99.6

99.8

100.0

99.9

100.0

100.0

 

% (#) dogs with no fleas

0.0

(0/34)

76.5

(26/34)

88.2

(30/34)

94.1

(32/34)

100.0

(34/34)

97.1

(33/34)

100.0

(33/33)

100.0

(33/33)

Afoxolanerc

27

Geomean

20.4

0.1

0.2

0.1

0.0

0.0

0.0

0.0

 

range

(5–178)

(0–4)

(0–2)

(0–3)

(0–1)

(0–0)

(0–1)

(0–0)

 

% control

 

99.3

99.2

99.6

99.9

100.0

99.9

100.0

 

% (#) dogs with no fleas

0.0

(0/27)

85.2

(23/27)

81.5

(22/27)

92.6

(25/27)

96.3

(26/27)

100.0

(27/27)

96.2

(25/26)

100.0

(23/23)

  1. aIn both groups, dogs were treated on day 0. In the afoxolaner group, dogs were also treated once between days 28–30 and once between days 54–60
  2. bDogs were orally administered fluralaner chews (Bravecto® Merck Animal Health) according to label directions
  3. cDogs were orally administered afoxolaner chewables (NexGard® Merial, Inc.) according to label directions
  4. dGeometric mean numbers of fleas in visual area counts on pets
  5. e{(Day 0 geometric mean animal area flea counts—day x geometric mean animal area flea counts)/day 0 geometric mean animal area flea counts)} x 100
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Parasites & Vectors

ISSN: 1756-3305

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