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Table 4 Fleas recovered in premises flea traps in naturally infested homes when dogs were administered either fluralaner or afoxolaner chews

From: Evaluation of fluralaner and afoxolaner treatments to control flea populations, reduce pruritus and minimize dermatologic lesions in naturally infested dogs in private residences in west central Florida USA

Treatment group # homes   Days post-Treatmenta
    Day 0 Day 7 Day 14 Day 21 Day 28–30 Day 40–45 Day 54–60 Day 82–86
Fluralanerb 17 Geomeand 19.2 1.5 0.5 1.2 0.1 0.1 0.0 0.0
  % controle   92.4 97.3 93.9 99.6 99.7 99.8 100.0
   range (6–122) (0–8) (0–5) (0–4) (0–1) (0–2) (0–1) (0–0)
Afoxolanerc 17 Geomean 14.0 1.9 1.7 1.4 0.5 0.3 0.3 0.1
  % control   86.5 88.0 90.2 96.7 98.2 97.8 98.9
  range (6–167) (0–10) (0–12) (0–23) (0–26) (0–11) (0–8) (0–1)
  1. a In both groups, dogs were treated on day 0. In the afoxolaner group dogs were also treated once between days 28–30 and once between days 54–60
  2. bDogs were orally administered fluralaner chews (Bravecto® Merck Animal Health) according to label directions
  3. cDogs were orally administered afoxolaner chewables (NexGard® Merial, Inc.) according to label directions
  4. dGeometric mean numbers of fleas recovered in two intermittent light flea traps averaged within households
  5. e{(Day 0 geometric mean trap flea counts—day x geometric mean trap flea counts)/day 0 geometric mean trap flea counts)} x 100