Treatment group | Â | Days post-Treatmenta
|
---|
 | Day 0 | Day 28–30 | Day 54–60 | Day 82–86 |
---|
 Fluralanerb
| # Dogs | 34 | 34 | 33 | 33 |
Mean CADESI - 4 Scored
| 51.5 | 20.4 | 15.2 | 9.1 |
STDEV | 17.53 | 8.99 | 9.95 | 5.29 |
Range | (9–80) | (0–39) | (0–40) | (0–20) |
Reductione
| Â | 60.4Â % | 70.5Â % | 82.3Â % |
 Afoxolanerc
| # Dogs | 27 | 27 | 26 | 23 |
Mean CADESI - 4 Scored
| 51.7 | 18.8 | 12.7 | 8.7 |
STDEV | 22.28 | 14.80 | 12.51 | 7.70 |
Range | (3–91) | (3–51) | (0–48) | (0–26) |
Reductione
| Â | 63.6Â % | 75.4Â % | 83.2Â % |
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aIn both groups dogs were treated on day 0. In the afoxolaner group, dogs were also treated once between days 28–30 and once between days 54–60
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bDogs were orally administered fluralaner chews (Bravecto® Merck Animal Health) according to label directions
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cDogs were orally administered afoxolaner chewables (NexGard® Merial, Inc.) according to label directions
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dArithmetic mean Canine Atopic Dermatitis Extent and Severity Index (CADESI)-4 scores (Olivry et al. Vet Dermatol 25(2):77–85, 2014)
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e{(Day 0 arithmetic mean CADESI-4 score – day x arithmetic mean CADESI-4 score)/day 0 arithmetic mean CADESI-4 score)} x 100