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Fig. 2 | Parasites & Vectors

Fig. 2

From: Identification of a novel β-adrenergic octopamine receptor-like gene (βAOR-like) and increased ATP-binding cassette B10 (ABCB10) expression in a Rhipicephalus microplus cell line derived from acaricide-resistant ticks

Fig. 2

Alignment of Rhipicehalus βAOR sequences and predicted structure of the βAOR protein. a Alignment of βAOR genomic sequences in Rhipicephalus spp. cell lines with published R. microplus strain NRFS (JN974909). Variations are highlighted in pink. b Alignment of βAOR amino acid sequences of published R. microplus strain NRFS (JN974909) and BME/CTVM6. The 12-aa insertion consists of an additional L (highlighted in red), followed by what appears to be duplication of LKTLALVTIIS (highlighted in blue). Green lines indicate the first transmembrane domain. c 2-dimensional representation of the R. microplus strain NRFS βAOR protein (left diagram) and the consequence of the 12-aa insertion (highlighted in red and blue) in the BME/CTVM6 βAOR protein (right diagram). The red line in the left diagram indicates the position of insertion. Membrane-spanning domains were predicted by the TMHMM Server at the Center for Biological Sequence Analysis, Technical University of Denmark, DTU (http://www.cbs.dtu.dk/services/TMHMM/) and 2 dimensional representation by TMRPres2D [31]

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Parasites & Vectors

ISSN: 1756-3305

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