Skip to main content

Table 1 Inhibitory activity of immune sera from the DNA vaccines on the in vitro formation of P. yoelii zygotes and ookinetes

From: Effects of transmission-blocking vaccines simultaneously targeting pre- and post-fertilization antigens in the rodent malaria parasite Plasmodium yoelii

Group

Median no. of parasites/well (range)

% inhibition of ookinetes

Zygotes

Ookinetes

Naïve mice

45.0 (39–51)

13.5 (8–17)

 

Vector control

42.0 (37–47)

11.5 (9–14)

14.8

Pys25

2.5 (1–4)a

0.0 (0–1)a

100

Pys48

4.5 (3–6)a

0.5 (0–1)a

96.3

Pys25 + Pys48

6.0 (4–8)a

0.5 (0–1)a

96.3

  1. aSignificant difference compared with the Naïve mice group at P < 0.05 by the Mann-Whitney U-Test