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Table 2 Transmission-blocking effect anti-Pys25 and Pys48/45 sera in direct mosquito feeding assay

From: Effects of transmission-blocking vaccines simultaneously targeting pre- and post-fertilization antigens in the rodent malaria parasite Plasmodium yoelii

  Vector control Pys25 Pys48 Pys25 + Pys48
N 26 27 28 28
# not infected 0 11 8 4
Prevalence (%)a 100.0 59.3 71.4 85.7
Median 221.0 3.0 23.5 18.5
Mean 224.6 3.6 26.4 24.9
Range 420 14 75 71
Reduction in Oocyst (%)b na 98.6 89.4 91.6
Reduction in Prevalence (%)c na 40.7 28.6 14.3
  1. aThe prevalence of infection was calculated by number of mosquitoes with oocysts/total mosquitoes dissected in each group
  2. b% reduction in oocyst was calculated as (mediancontrol–medianpcDNA3.1 + plasmid)/mediancontrol × 100
  3. c% reduction in prevalence was calculated as (% prevalencecontrol–% prevalencepcDNA3.1 + plasmid)/  % prevalencecontrol × 100