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Table 1 Larval bioassay with deltamethrin in Aedes aegypti strains and hybrids

From: Additive effect of knockdown resistance mutations, S989P, V1016G and F1534C, in a heterozygous genotype conferring pyrethroid resistance in Aedes aegypti in Thailand

Straina

kdr genotype

Synergistb

LC50 (95 % CI) μgl-1

RRc

Slope ± SD

χ 2

P d

UPK-R

PP + GG + FF

–

6.98 (6.10–8.04)

53.69

2.05 ± 0.14

5.93 (n = 6, df = 5)

0.204

UPK-R

PP + GG + FF

BNPP

6.85 (6.26–7.44)

52.69

3.34 ± 0.29

6.42 (n = 5 df = 4)

0.092

UPK-R

PP + GG + FF

PBO

4.93 (4.24–5.70)

37.92

1.88 ± 0.14

7.82 (n = 6, df = 5)

0.098

F1 (PMD-Rf × UPK-Rm)

SP + VG + FC

–

3.58 (3.21–3.95)

27.54

3.12 ± 0.23

9.39 (n = 6, df = 5)

0.051

F1 (PMD-Rf × UPK-Rm)

SP + VG + FC

BNPP

3.44 (3.10–3.78)

26.46

3.15 ± 0.27

5.21 (n = 5, df = 4)

0.156

PMD-R

SS + VV + CC

–

1.72 (1.55–1.90)

13.23

3.02 ± 0.19

8.13 (n = 7, df = 6)

0.149

F1 (PMD-Rf × UPK-Rm)

SP + VG + FC

PBO

1.52 (1.35–1.73)

11.69

2.57 ± 0.17

9.22 (n = 6, df = 5)

0.055

PMD-R

SS + VV + CC

BNPP

1.44 (1.31–1.59)

11.07

2.79 ± 0.19

3.85 (n = 6, df = 5)

0.426

PMD-R

SS + VV + CC

PBO

0.72 (0.63–0.81)

5.53

2.49 ± 0.23

3.86 (n = 6, df = 5)

0.275

F1 (UPK-Rf × PMDm)

SP + VG + FF

–

0.57 (0.51–0.63)

4.38

2.47 ± 0.16

8.47 (n = 7, df = 6)

0.131

F1 (UPK-Rf × PMDm)

SP + VG + FF

BNPP

0.48 (0.44–0.54)

3.69

2.67 ± 0.18

3.29 (n = 7, df = 6)

0.510

PMD

SS + VV + FF

–

0.13 (0.12–0.15)

1

3.09 ± 0.25

1.45 (n = 5, df = 4)

0.690

F1 (UPK-Rf × PMDm)

SP + VG + FF

PBO

0.08 (0.07–0.09)

0.62

3.28 ± 0.24

8.57 (n = 6, df = 5)

0.727

  1. a f female, m male
  2. b PBO piperonyl butoxide, BNPP bis(4-nitrophenyl)-phosphate
  3. cResistance ratio is based on comparison with the PMD strain
  4. dAll P-values > 0.05 indicating that the plots of concentration-mortality response are normally distributed, and hence the LC50 values are valid