Skip to main content

Table 1 PKDL - differences between Africa and Asia

From: The immunology of post-kala-azar dermal leishmaniasis (PKDL)

  Asia Africa
Clinical type most common macular papular
Frequency after VL 10–20 % 50–60 %
Infective to sand flies yes yes
Transmission of VL anthroponotic anthroponotic and zoonotic
Interval after VL 0–3 years, or morea 0–13 months
Self-cure yes, probably yes
Occurs without previous VL yes yes
Occurs with VL simultaneouslyb yes yes
Occurs with mucosal involvement yes yes
Treatment policy all are treated chronic > 6 months or severe PKDL are treated
Treatment miltefosine SSG or AmBisome
Marker for cure clinical clinical
  1. arecent data show that up to 30 % of PKDL in Asia occurs within 12 months after treatment for VL
  2. bthis is also called para-kala-azar dermal leishmaniasis