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Table 2 Identification of host-derived proteins with identical tryptic peptides to I. scapularis tick homologues

From: The intracellular bacterium Anaplasma phagocytophilum selectively manipulates the levels of vertebrate host proteins in the tick vector Ixodes scapularis

ID

Description

Unique host-derived peptides

P31081

HSP60

ALMLQGVDLLADAVAVTMGPK

VGGTSDVEVNEK

VGGTSDVEVNEKKDR

P0CB32

HSP70

FDLTGIPPAPR

RKELEQVCNPIITK

P68432

Histone H3.1

RVTIMPKDIQLAR

SAPATGGVK

SAPATGGVKKPHRYRPGTVALR

F1MN93

TOP1 uncharacterized protein

AGNEKEEGETADTVGCCSLR

HLQDLMEGLTAK

P62808

Histone H2B type 1

AMGIMNSFVNDIFER

EIQTAVRLLLPGELAK

EIQTAVR

ESYSVYVYK

SRKESYSVYVYK

STITSREIQTAVRLLLPGELAK

STITSREIQTAVR

VLKQVHPDTGISSK

W5PLV3

RAB5B uncharacterized protein

TAMNVNDLFLAIAK

P62803

Histone H4

None

Q9TTS3

Acetyl-CoA carboxylase 1

None

  1. To confirm the origin for selected differentially represented proteins (Table 1), all of the peptides used to identify the proteins sharing tryptic peptides with I. scapularis proteins were revised. The peptides unique for host-derived proteins are shown. For protein P62803, we could not define the origin due to 100 % homology between sheep and tick proteins. For protein Q9TTS3, all peptides used for identification were identical in both host and tick-derived proteins