Table 1 Empirically determined paramyosin epitopes interacting with components of the immune system of various organisms (nematodes, platyhelminths and arthropods)
From: Paramyosin of canine Onchocerca lupi: usefulness for the diagnosis of a neglected zoonotic disease
Species | Type | Epitopes detected (amino acids) | Part of the protein | Reference |
|---|---|---|---|---|
Haemaphysalis longicornis | - | L71-E92 | N-terminal | [42] |
Onchocerca volvulus | B-cell | A253-D265 | N-terminal | [62] |
Schistosoma japonicum | B-cell | I363-A366 | Middle | [63] |
L362-A366 | ||||
Schistosoma mansoni | T- and B-cell | M1-T25 | Whole | [72] |
L481-E500 | ||||
N355-K367 | ||||
T-cell | T6-P22 | N-terminal | [64] | |
N366-D382 | Middle | |||
Y210-S226 | ||||
Complement | A744-M866 | C-terminal | [43] | |
B-cell | G19-L27 | Whole | [72] | |
L66-G71 | ||||
D93-N98 | ||||
L155-E166 | ||||
K232-A239 | ||||
E275-H283 | ||||
E305-E312 | ||||
E326-A338 | ||||
R372-E377 | ||||
Q400-L404 | ||||
L460-L467 | ||||
R502-E511 | ||||
R579-A590 | ||||
L686-H695 | ||||
E766-I774 | ||||
Q798-E804 | ||||
R814-M829 | ||||
L852-G859 | ||||
T-cell | V10-Y17 | Whole | [72] | |
Q58-R65 | ||||
V123-D136 | ||||
L178-L186 | ||||
L196-E211 | ||||
Q259-E275 | ||||
L439-R446 | ||||
T516-Y524 | ||||
V630-V637 | ||||
K787-A794 | ||||
V805-K812 | ||||
Taenia solium | - | R10-T16 | N-terminal | [65] |
T-cell | D176-L192 | [66] | ||
Trichinella spiralis | Antibody | E88-E107 | N-terminal | [67] |