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Table 3 Acute toxicity in L3/L4 instars of A. arabiensis and A. gambiae (s.s.) resulting from treatment of larvae with the active green tea fraction for 24, 48 and 72 h. Data presented below indicates the percentage means (± S.D) of mortality rates of mosquito larvae exposed to different concentrations of bioactive fraction of C. sinensis extract for different time periods (24, 48 and 72 h). Five replicates were included in the study. Half maximal lethal concentrations (LC50) for each dose exposure period have been determined at their 95 % confidence intervals. The mosquito larvae exhibited significant susceptibility to the bioactive fraction at P < 0.05

From: Potential of Camellia sinensis proanthocyanidins-rich fraction for controlling malaria mosquito populations through disruption of larval development

  Concentration (ppm) Lethal concentration (ppm)
Time 25 10 5 2.5 1 Control LC50 95 % CI
An. arabiensis*
 24 h 100 ± 0.00 62 ± 10.37 20 ± 6.12 13 ± 9.08 0 ± 0.00 0 ± 0.00 7.37 3.98–12.64
 48 h 100 ± 0.00 69 ± 9.62 33 ± 9.08 17 ± 10.37 0 ± 0.00 0 ± 0.00 6.22 3.04–11.06
 72 h 100 ± 0.00 76 ± 9.62 43 ± 9.08 25 ± 10.00 0 ± 0.00 0 ± 0.00 5.20 2.17–9.70
An. gambiae (s.s.)*
 24 h 100 ± 0.00 69 ± 17.10 42 ± 8.37 25 ± 14.58 0 ± 0.00 0 ± 0.00 5.52 2.68–9.65
 48 h 100 ± 0.00 78 ± 2.24 56 ± 12.94 32 ± 14.40 0 ± 0.00 0 ± 0.00 4.45 1.55–8.71
 72 h 100 ± 0.00 88 ± 9.08 70 ± 11.18 38 ± 14.40 0 ± 0.00 0 ± 0.00 3.60 0.29–8.71
  1. Data presented as mean ± SD of five replicates
  2. Abbreviations: LC 50 lethal concentration that killed 50 % of test mosquito larvae population, CI confidence interval
  3. *Mean values are not significantly different P ≤ 0.05 (ANOVA)