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Fig. 4 | Parasites & Vectors

Fig. 4

From: Increased expression of ATP binding cassette transporter genes following exposure of Haemonchus contortus larvae to a high concentration of monepantel in vitro

Fig. 4

Rhodamine efflux from larvae following monepantel pre-exposure. R-123 efflux was measured after exposure of L3 stage larvae to MPL250μg/ml or MPL2.5μg/ml, compared to DMSO-treated controls; Kirby isolate: a at 3 h and b at 6 h; WAL isolate: c at 3 h and d at 6 h. Significant increase in R-123 efflux compared to controls is indicated by * (P < 0.05). The columns represent mean ± standard error of the mean (SEM), n = 6 (pooled data from three separate experiments, each with assays in duplicate)

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