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Fig. 6 | Parasites & Vectors

Fig. 6

From: Increased expression of ATP binding cassette transporter genes following exposure of Haemonchus contortus larvae to a high concentration of monepantel in vitro

Fig. 6

Stability of IVM tolerance in WAL L3 stage larvae pre-treated with monepantel. Sensitivity of WAL L3 stage larvae to IVM (a) or LEV (b) was measured using migration assays following pre-exposure for 3 h to MPL250μg/ml, followed by 24 h in water only, compared to L3 exposed to DMSO for 3 h, followed by water for 24 h. DMSO pre-exposure shown with solid lines and closed symbols, MPL pre-exposure shown with dashed lines and open symbols. The data points marked with * show significant differences (P < 0.05) in percent migration between MPL- and DMSO- pre-exposure groups (t-test). Each data point represents mean ± standard error of the mean (SEM), n = 9 (pooled data from three experiments, each with assays in triplicate)

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