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Table 3 Results of the final multivariable Cox proportional hazards regression model for T. canis reinfection

From: Recurrent patent infections with Toxocara canis in household dogs older than six months: a prospective study

  No. of dogs No. of dog-months at risk No. of observed RPIs HR 95 % CI P-value
Age group
 6–12 months 49 110 30 Ref.    
 1–7 years 202 2,211 170 0.85 0.49 1.46 0.552
  > 7 years 96 926 84 0.87 0.47 1.62 0.663
Sex
 Male 121 1,400 125 Ref.    
 Female 162 1,847 159 1.27 0.91 1.77 0.160
Coprophagy
 No 118 1,234 84 Ref.    
 Yes 170 2,013 200 1.09 0.74 1.59 0.674
Sampling season
 Summer 237 777 57 Ref.    
 Winter 220 612 95 1.68 1.15 2.46 0.008
 Autumn 239 857 50 1.30 0.82 2.08 0.266
 Spring 244 1,001 82 1.43 0.96 2.14 0.079
Taking corticosteroids
 No 265 3,036 263 Ref.    
 Yes 25 211 21 2.38 1.09 5.19 0.029
Frequency of dog’s faeces removal/disposal
 Never 32 351 48 Ref.    
 Sometimes 160 1,903 164 0.54 0.33 0.86 0.01
 Always 89 993 72 0.54 0.32 0.91 0.02
Change in dog’s main purpose/use
 No 280 3,238 281 Ref.    
 Yes 8 9 3 10.84 1.14 103.21 0.038
Having neurologic conditions
 No 279 3,188 283 Ref.    
 Yes 9 59 1 0.11 0.02 0.74 0.023
Having orthopaedic conditions
 No 262 2,891 260 Ref.    
 Yes 45 356 24 0.55 0.28 1.06 0.074
Owner usually buys anthelmintic drugs at veterinary clinics
 No 134 1,464 107 Ref.    
 Yes 147 1,783 177 1.52 1.10 2.11 0.011
Time since last deworming (months)a 1.003 1.001 1.005 < 0.0001
  1. aContinuously time-varying variable let interact with the underlying time variable
  2. Abbreviations: HR hazard ratio; 95 % CI, 95 % confidence interval; RPI recurrent patent infection; Ref. reference category