Table 2 Therapeutic efficacy of IVM LAI against natural infestations of first-stage and second- and third-stage larvae of Hypoderma spp
From: Treatment and control of bovine hypodermosis with ivermectin long-acting injection (IVOMEC® GOLD)
Study | Treatmenta (Study day) | NI/NGb | GMc (Range) | Efficacyd (%) | Z-value | P-valuee |
|---|---|---|---|---|---|---|
Live Hypoderma lineatum larvae | ||||||
1. Italy | Control (day 0) | 9/11 | 2.8 (0–17) | – | ||
IVM LAI L1f (day 0) | 0/11 | 0 | 100 | 3.6150 | 0.0003 | |
IVM LAI L2/L3g (day 84) | 0/11 | 0 | 100 | 3.6150 | 0.0003 | |
Live Hypoderma bovis larvae | ||||||
2. Germany | Control (day 0) | 7/10 | 1.5 (0–8) | – | – | |
IVM LAI L1 (day 0) | 0/10 | 0 | 100 | 3.0729 | 0.0021 | |
IVM LAI L2/L3 (day 125) | 0/10 | 0 | 100 | 3.0729 | 0.0021 | |
3. USA | Control (day 0) | 6/8 | 1.8 (0–22) | – | – | |
IVM LAI L1 (day 0) | 0/8 | 0 | 100 | 2.8387 | 0.0045 | |