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Table 1 Poultry red mite mortality 48 h after feeding on blood enriched with antibodies. Values shown are for all recombinant proteins and native protein extracts evaluated at Moredun Research Institute thus far. Data were normalised by subtracting the percentage mortality of the mites in the control groups from the mortality of the mites in the test groups

From: Characterisation of tropomyosin and paramyosin as vaccine candidate molecules for the poultry red mite, Dermanyssus gallinae

Vaccine antigen

Antigen type

Increase in percentage mortality at 48 h after feeding (%)

Reference

Whole SME

Native

24.0*

[20]

IEX-Group-4

Native

23.5*

[20]

Deg-VIT-1

Recombinant

21.9*

[20]

Der g 11

Recombinant

20.1*

Present study

IEX-Group-1

Native

19.5*

[20]

Deg-HGP-1

Recombinant

18.9*

[20]

Deg-PUF-1

Recombinant

18.4*

[20]

Der g 10

Recombinant

16.5*

Present study

Deg-CPR-1

Recombinant

14.5

[20]

IEX-Group-3

Native

13.0*

[20]

Deg-SRP-1

Recombinant

12.3*

[20]

IEX-Group-5

Native

11.4*

[20]

PBS-soluble

Native

10.1*

[36]

Dg-CatD-1

Recombinant

6.9*

[39]

Deg-ASP-1

Recombinant

5.6

[20]

Dg-HRF

Recombinant

4.1*

[37]

Deg-GPD-1

Recombinant

4.1

[20]

Deg-PUF-3

Recombinant

3.5

[20]

Dg-CatL-1

Recombinant

2.6*

[39]

Membrane associated

Native

2.2

[36]

Deg-PUF-2

Recombinant

0.6

[20]

Urea- soluble

Native

0.2

[36]

Integral membrane

Native

-1.5

[36]

IEX-Group-2

Native

-4.2

[20]

Deg-SRP-2

Recombinant

-8.2

[20]

  1. *Statistically significant difference (P < 0.05) between mortalities in the control and antigen test groups in the original study