Fig. 1

Candidate GPCRs identified from the S. mansoni genome. a Workflow for mining candidate GPCRs from the S. mansoni genome. b Venn diagram showing comparison of three bioinformatics tools (see Methods) listed to define GPCRs. c RT-PCR detection of S. mansoni miracidium GPCR transcripts at 6 h post-hatch. +, represents presence of amplicon