Skip to main content

Table 3 Validation of homology models of L. donovani Inl-A-like proteins

From: Identification of internalin-A-like virulent proteins in Leishmania donovani

L. donovani Inl-A-like proteins E9B7L9 E9BMT7 E9BUL5
Predicted Inl-A-like Region 212–573 394–757 386–782
Sequence similarity index
 Whole Sequence Identity with Inl-A (UniProt ID: PODJMO) 18 % 15 % 16.8 %
 LRR Region Sequence Identity with Inl-A (UniProt ID: PODJMO) 21 % 20 % 22 %
 LRR Region Sequence Similarity with Inl-A (UniProt ID: PODJMO) 41.7 % 41.2 % 33.4 %
Structure Similarity Index  
 Root Mean Square Deviation (RMSD) [Å] with Inl-A (PDB ID: 1O6S, chain A) 1.2 1 1.5
Stereo-chemical Evaluation
 Ramachandran Plot [47] Favored 320 (88.9 %) 319 (88.1 %) 334 (84.6 %)
Allowed 37 (10.3 %) 39 (10.8 %) 53 (13.4 %)
Outlier 3 (0.8 %) 4 (1.1 %) 8 (2.0 %)
 Verify3d [45, 46] Passed (93.65 % of the residues had an averaged 3D–1D score > = 0.2) Passed (91.21 % of the residues had an averaged 3D–1D score > = 0.2) Passed (88.92 % of the residues had an averaged 3D–1D score > = 0.2)