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Table 2 Time to onset of activity and speed of kill using two different efficacy calculation methods for acaricidal treatments over the 48 h following administration to dogs infested with adult R. sanguineus (s.l.) 48 h prior to treatment

From: A comparative laboratory trial evaluating the immediate efficacy of fluralaner, afoxolaner, sarolaner and imidacloprid + permethrin against adult Rhipicephalus sanguineus (sensu lato) ticks attached to dogs

Treatment Time to onset of activity
(h)
Efficacy at onset time (%) Speed of kill (time to 90% “live attached” efficacy)
(h)
Efficacy (“live attached”) at “speed of kill” time point (%) Speed of kill (time to 90% “live attached and free” efficacy)
(h)
Efficacy (“live attached and free”) at “speed of kill” time point (%) Time to 100% efficacy (the time was the same for both calculation types) (h)
Imidacloprid + Permethrin 2 36.9 Not attained Not attained Not attained Not attained Not attained
Fluralaner 4 60.2 8 99.7 8 98.2 12
Sarolaner 4 48.2 8 94.7 12 100 12
Afoxolaner 8 90.8 8 90.8 12 97.9 48