Table 2 Time to onset of activity and speed of kill using two different efficacy calculation methods for acaricidal treatments over the 48 h following administration to dogs infested with adult R. sanguineus (s.l.) 48 h prior to treatment
Treatment | Time to onset of activity (h) | Efficacy at onset time (%) | Speed of kill (time to 90% “live attached” efficacy) (h) | Efficacy (“live attached”) at “speed of kill” time point (%) | Speed of kill (time to 90% “live attached and free” efficacy) (h) | Efficacy (“live attached and free”) at “speed of kill” time point (%) | Time to 100% efficacy (the time was the same for both calculation types) (h) |
|---|---|---|---|---|---|---|---|
Imidacloprid + Permethrin | 2 | 36.9 | Not attained | Not attained | Not attained | Not attained | Not attained |
Fluralaner | 4 | 60.2 | 8 | 99.7 | 8 | 98.2 | 12 |
Sarolaner | 4 | 48.2 | 8 | 94.7 | 12 | 100 | 12 |
Afoxolaner | 8 | 90.8 | 8 | 90.8 | 12 | 97.9 | 48 |