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Fig. 7 | Parasites & Vectors

Fig. 7

From: A mitochondrial HSP70 (HSPA9B) is linked to miltefosine resistance and stress response in Leishmania donovani

Fig. 7

2D-DIGE quantitative analysis of the membrane-associated proteome of HSPA9B-mCherry transgenic L. donovani. a Protein extracts were enriched for mitochondrial membrane and lumen components using the Qproteome Cell Compartment Kit. A representative gel image is shown. b Spots ID 1 and 3 are under- and overrepresented, respectively, in the HSPA9B-mCherry line and expression profiles with significant statistics is shown along with representative 3D regions of the gels. c After image analysis, spots were excised and identified by mass spectrometry. The table shows the Fold Change (FC) HSPA9B-mCherry/WT ratio, as well as Mascot and P-values for spots ID1 and ID3

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