Table 4 Phylogeographic studies using quantitative analytical methods
From: Geographical, landscape and host associations of Trypanosoma cruzi DTUs and lineages
Article | Hypothesis/Aim | Parasite population | Sample size | Geographical scale | Temporal scale (yrs) | Population genetic analysis | Outgroup | Statistical analytical method |
|---|---|---|---|---|---|---|---|---|
Llewellyn et al. [67] | Population genetics of sylvatic TcIIc from South America (diversity, spatial structure and climatic associations) | Isolates | 53 | Colombia, Brazil, Venezuela, Bolivia and Paraguay | 25 | GPI sequencing/ microsatellite | T. c. marinkellei | NJ/Genetic diversity (Ar/He/Ho/HD)/Mantel test |
Llewellyn et al. [68] | Population genetics of sylvatic TcI/diversity associated with epidemiological relevance | Isolates | 135 | Americas | 22 | Microsatellite | none | Genetic diversity (Ar/He/Ho/HD)/Mantel test |
Messenger et al. [77] | Population structure, hybridization and role for humans in parasite dispersal | Isolates | 199 | Bolivia | 6 | Microsatellite and maxicircle | DTUI | Population genetic parameters/NJ/Fst/ Mantel test/ML |
Lima et al. [78] | Genetic diversity, genetic exchange and impact of ecological disturbance | Isolates | 107 | Brazil | md | Microsatellite and maxicircle | DTUIV | Genetic diversity parameters/ML |
López-Cancino et al. [80] | Relationships between parasite diversity, host metacommunities, and vectors in a human-disturbed gradient | Original | 81 | Yucatán, México | 5 | Mini-exon sequencing | none | Network analysis/Phylogenetic (ML) |
Ocaña-Mayorga et al. [81] | Genetic subdivision by transmission cycle, and anthropogenic dispersal between communities and panmixia among strains | Isolates | 81 | Loja Province, Ecuador | md | Microsatellite | none | Genetic diversity (Ar/PA/FIS/FST)/ AMOVA/DAS/Mantel test |
Rodriguez et al. [84] | Transmission dynamics of Tc genotypes | Original | 121 | Colombia | md | LSSP-PCR, Southern Blot | DTUII | Nei's distance and NJ/AMOVA |
Herrera et al.[140] | Sequence variability of the SL-IR | Isolates | 244 | 11 Latin American countries | md | Mini-exon sequencing | none | Network/PCA |
Herrera et al. [145] | Genotype diversity of Tc in Louisiana | Isolates | 15 | New Orleans, Louisiana (USA) | 4 | Miniexon sequencing | none | Phylogenetic (ML) |
Venegas et al. [143] | Geographical structure and genetic differences among or within lineages in Chilean Tc populations | Original | 64 | Chile | 2 | Microsatellite | none | Fisher's exact test, AMOVA, FST, Mantel test |
Zumaya-Estrada et al. [141] | Dispersal among domestic transmission cycles of Tcdom in northern South America, sister group of North American strains | Isolates | 72 | Americas | md | Microsatellite | DTUIII, DTUIV | Genetic diversity/Bayesian topology/NJ/MYA geographic calibration point |