Skip to main content
Fig. 4 | Parasites & Vectors

Fig. 4

From: The immunological characteristics and probiotic function of recombinant Bacillus subtilis spore expressing Clonorchis sinensis cysteine protease

Fig. 4

Antibody titres of IgG and isotopes triggered by rCsCP and coat proteins of B.s-CotC-CsCP spores via subcutaneous immunization route. ELISA evaluation of the CsCP specific IgG a and IgG1/IgG2a c levels in mouse sera after subcutaneous immunization with rCsCP. b Antibody titres of IgG induced by rCsCP at week 6. The levels of CsCP specific IgG d and IgG1/IgG2a f in the sera of mice subcutaneously immunized with spore coat proteins of B.s-CotC-CsCP. Antibody titres of IgG evoked by spore coat proteins of at week 6 were also assayed by ELISA e. Data were displayed as the mean ± SD. *P < 0.05; **P < 0.01; ***P < 0.001. Abbreviations: B.s-CotC-CP, WB600 containing pEB03-CotC-CsCP; B.s-CotC, WB600 containing pEB03-CotC; rCP, purified rCsCP

Back to article page