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Table 1 Host-to-tick transmission of B. afzelii and the spirochete load of the infected I. ricinus nymphs are shown for the ten combinations of strain (A3 or A10) and the age of infection (2, 34, 66, 94 and 128 days). The probability of transmission shows the number of infected nymphs divided by the total number of nymphs analysed, and the corresponding percentage of infected nymphs. The spirochete load presents the mean spirochete load and the 95% confidence interval (CI) for the subset of infected nymphs

From: Comparison of the lifetime host-to-tick transmission between two strains of the Lyme disease pathogen Borrelia afzelii

Strain Age of infection (days) Transmission Spirochete load
Infected nymphs/total nymphs (%) Meana 95% CI
A3 2 14/105 (13.3) 2,591 1,711–3,924
A3 34 75/100 (75.0) 10,496 8,163–13,496
A3 66 54/95 (56.8) 9,064 7,301–11,251
A3 94 57/90 (63.3) 9,853 7,822–12,411
A3 128 62/90 (68.9) 8,100 6,811–9,633
A10 2 98/190 (51.6) 6,436 5,548–7,465
A10 34 118/130 (90.8) 19,250 17,214–21,528
A10 66 73/118 (61.9) 18,488 15,971–21,402
A10 94 88/128 (68.9) 32,087 28,593–36,009
A10 128 79/128 (61.7) 18,806 17,058–20,735
Total   718/1,174 (61.2)   
  1. aFor each of the ten combinations of strain and age of infection, the geometric mean spirochete load in the nymphal tick was calculated for each mouse (uninfected nymphs were excluded). For strains A3 and A10, the geometric mean nymphal spirochete load and the 95% confidence interval are based on 10 and 13 mice, respectively