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Fig. 4 | Parasites & Vectors

Fig. 4

From: RNAi reveals proteins for metabolism and protein processing associated with Langat virus infection in Ixodes scapularis (black-legged tick) ISE6 cells

Fig. 4

Cellular pathways of I. scapularis proteins and possible roles in the LGTV life-cycle inferred from RNAi data. VNN, MDH2, PARP, and Hypo195 exhibited increased expression following LGTV infection only (blue text). FAH, ERP29, ALDH, CMPK, ACAT1, and Hypo576 (magenta text) exhibited increased expression following LGTV infection and/or UV-LGTV treatment [4]. CMPK: orange arrow, VNN: red arrows, ACAT1: blue arrows, FAH: green arrows, ALDH: purple arrow, MDH2: brown arrow, ERP29: black arrow, Hypo576: gray arrows, and Hypo195: pink arrows. Cellular pathways were inferred based on the classification of ISE6 proteins by KEGG PATHWAY analysis and RNAi data (pre-treatment and post-treatment with dsRNA; Fig. 2b-d; Table 2)

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