Fig. 2From: Immune and biochemical responses in skin differ between bovine hosts genetically susceptible and resistant to the cattle tick Rhipicephalus microplus Differentially expressed genes (DEG) found in common across comparisons of tick-infested skin. Genes involved in common in anti-tick responses as well as potential signatures for tick resistance were identified. a Venn diagram showing number of DEGs between Str skins versus Lar or Nym skins comparisons within each breed (intra-breed comparison). Numbers inside brackets indicate the number of genes that were upregulated (red), downregulated (green) or of mixed pattern (blue). b Hierarchical clustering of expression pattern of six genes found in both overlaps of intra-breed comparisons shown in Fig. 2a. Color bar represent the log2 transformation of fold change values (-1.0 to 3.0) from infested skins when compared to normal skin within same breed; green and red means downregulated and upregulated genes, respectively. Abbreviations: S, tick-susceptible hosts; R, tick-resistant hosts; Bsl, baseline skin skin; Str, stressed skin; Lar, larvae-infested skin; Nym, nymph-infested skinBack to article page