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Fig. 3 | Parasites & Vectors

Fig. 3

From: Immune and biochemical responses in skin differ between bovine hosts genetically susceptible and resistant to the cattle tick Rhipicephalus microplus

Fig. 3

Functional analysis of genes found in common across comparisons of tick-infested skin. The functional analyses were done with MetaCore software (https://portal.genego.com/, Thomson Reuters). The enrichment analyses showed Role of fibroblast and keratinocytes in the elicitation phase of allergic contact dermatitis as the most significant pathway map (P = 2.095e-7, 1.0970e-5 FDR). This pathway map showed functional interaction of 3 genes (thermometers) found in both overlaps of intra-breed comparisons shown in Fig. 2b. Colors inside of thermometers indicate that genes were upregulated (red) or downregulated (blue) in tick-infested skin from both types of hosts. Numbers inside of thermometers indicate the comparisons in which genes are DEG: 1, comparison between stressed and nymph-infested skin from tick-resistant hosts; 2, comparison between stressed and nymph-infested skin from tick-susceptible hosts; 3, comparison between stressed and larvae-infested skin from tick-susceptible hosts; 4, comparison between stressed and larvae-infested skin from tick-resistant hosts

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Parasites & Vectors

ISSN: 1756-3305

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