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Table 4 Adverse event incidence by age group, PZQ 40 mg/kg

From: Efficacy and safety of praziquantel 40 mg/kg in preschool-aged and school-aged children: a meta-analysis

Adverse event Pre-school aged School-aged
No. of study arms No. of subjects Incidence (95% CI) No. of study arms No. of subjects Incidence (95% CI)
% Lower bound Upper bound % Lower bound Upper bound
Any adverse event (at least one) 1 243 34.2 28.2 40.2 8 1,342 54.2 37.0 72.2
Drowsiness 2 503 29.1 28.0 30.1 2 285 42.4 35.8 49.0
Dizziness 3 737 22.4 1.3 33.9 13 3,132 9.3 5.4 14.1
Fatigue 3 737 13.3 0.9 20.9 3 781 13.2 0.4 28.9
Itching/rash 2 503 8.6 8.0 9.1 8 1,504 5.5 2.3 9.3
Nausea 3 737 7.8 2.1 12.6 12 3,058 12.9 6.4 20.2
Abdominal pain 3 737 7.2 3.0 9.4 19 3,495 33.4 22.6 43.9
Vomiting 3 737 6.8 1.7 9.6 15 2,911 7.9 3.8 13.2
Headache 3 737 4.4 0.4 6.7 17 3,314 16.6 9.8 24.0
Diarrhoea 3 737 4.3 2.6 6.3 16 3,106 12.1 6.5 19.3
  1. Abbreviations: CI confidence interval