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Table 8 Effect of silencing on the length (mean ± standard deviation) of male and female worms recovered from jirds infected with in vitro siRNA-treated (bmugm specific, negative) and untreated L3

From: RNA interference mediated knockdown of Brugia malayi UDP-Galactopyranose mutase severely affects parasite viability, embryogenesis and in vivo development of infective larvae

Groups

Worm length (cm)

Female worms

Male worms

Medium control

3.7 ± 0.09

1.75 ± 0.06

Scrambled siRNA

3.7 ± 0.08

1.72 ± 0.1

siRNA1 + 2

3.5 ± 0.07**

1.58 ± 0.05*

  1. *P < 0.05; **P < 0.01