Fig. 2
From: Experimental evaluation of Peromyscus leucopus as a reservoir host of the Ehrlichia muris-like agent
Lung tissue from white-footed mice acutely infected with EMLA. Images a–d show sections stained with hematoxylin and eosin, revealing various pathological signs including (a) marked perivascular edema (asterisk); (b) mononuclear perivascular infiltration in lung tissue (asterisk) and peripheral alveolar edema; (c) alveolar edema (asterisk), alveolar macrophages (arrowheads) and multinucleate macrophage (arrow); (d) enlarged vascular endothelial cells containing morulae (arrows). In situ hybridization was performed on section (e) to identify morulae within endothelial cells of pulmonary vasculature. EMLA is labeled red, cell nuclei are stained blue. Scale-bars: a, b, 200 μm; c, e, 100 μm; d, 50 μm