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Table 2 Parameter values for cysticercosis model (values are expressed per month). Minimum and maximum values were used for the sensitivity analysis

From: Assessing the impact of intervention strategies against Taenia solium cysticercosis using the EPICYST transmission model

Parameter

Value

Minimum

Maximum

Derivation (min, max)

Reference

Human population size

10,000

–

–

–

–

Pig population size

2000

–

–

–

–

d H

0.0015

0.0013

0.0018

Average human life expectancy of 54 years (46, 64)

[56]

d P

0.083

0.042

0.17

Average age at slaughter: 1 year (0.5, 2)

[14, 28, 57]

d E a

2

0.083

4

Average period of persistence of eggs in environment: 2 weeks (1 week, 3 months)

[50–53, 58]

α

0.042

0.017

0.17

Average lifespan of T. solium: 2 years (0.5, 5)

[59, 60]

Ï„ a

2.36 × 10-10

0.25Ï„

4Ï„

–

b

Ï•

0.8

0.1

0.9

–

[61]

δ

960,000

640,000

1,800,000

–

[60, 62]

ε

0.01

0.0075

0.0125

–

[63]

χ

0.5

0.083

0.68

Assumes 1 pork meal = 200 g; 1.2 kg per capita per annum (0.2 kg, 3.4 kg) = an average 6 pork meals per year

[64]

Ï€ L a

0.0084

0.25Ï€ L

4Ï€ L

–

b

r consumption

-0.25

-0.66

0

–

c

r infection

1

0

2

–

c

θ a

2.45 × 10-11

0.25θ

4θ

–

b

r Cysticercosis

1

0

4

–

[65]

η

0.0277

0.00167

0.083

Average duration of cysticercosis infection in humans: 3 years (1, 50)

[66]

  1. aIndicates that a uniform distribution was specified for the LHS-PRCC, a triangle distribution was used for all other parameters
  2. bParameter values were derived by equilibrium analysis
  3. cWhere evidence in the literature was scarce to motivate parameter values, the values chosen were based upon expert opinion of plausible and conservatively wide ranges and their influence was further explored in the sensitivity analysis