Table 1 Chronology of the naming of ‘K’ or ‘rK’ antigens used for serological diagnosis of visceral leishmaniasis
From: Diagnostic antigens for visceral leishmaniasis: clarification of nomenclatures
Year | Reference | Antigen | Species | Parent protein | Reported origin | Strain details | GenBank accession number |
|---|---|---|---|---|---|---|---|
1993 | Burns et al. [2] | rK39 | L. infantum (syn. L. chagasi) | LcKin (kinesin-related) | Brazil | MHOM/BR/82/BA-2,C1 | L07879 |
1994 | Tolson et al. [3] | KMP-11 | L. donovani | Kinetoplastid membrane protein | Not given | LD3, derivative of 1S2D clonea | S77039a |
1999 | Alce et al. [4] | HASPB1/HASPB2 | L. donovani | HASP | Ethiopia | MHOM/ET/67/L28 isolate LV9 | AJ011810/ AJ011809 |
1999 | Bhatia et al. [5] | K9/K26 | L. infantum (syn. L. chagasi) | Hydrophilic protein (see text) | Brazil | MHOM/BR/74/PP75 | AF131227/ AF131228 |
2006 | Sivakumar et al. [6] | Ld-rKE16 | L. donovani | Kinesin | India | MHOM/IN/98/KE16 | AY615886 |
2007 | Gerald et al. [7] | LdK39 | L. donovani | Kinesin LdK39 | Sudan | MHOM/SD/62/1S-CL2D | DQ831678 |
2007 | Takagi et al. [9] | rKRP42 | L. donovani | Kinesin | India/Bangladesh | MHOM/IN/80/DD8 | AB256033 |
2010 | Pattabhi et al. [8] | rK28 | L. donovani | HASPB1/LdK39/ HASPB2 | Sudan/Ethiopia | Synthetic gene | HM594686 |
2013 | Abass et al. [10] | rKLO8 | L. donovani | Kinesin | Sudan | Lo8 | KC788285 |
2015 | Vallur et al. [11] | rK18 | Not given | Not given | Not given | Not given | Not given |
2016 | Vallur et al. [12] | rKR95 | L. donovani | Kinesin-related protein | Bangladesh | Not applicable; see text. | GI112293604 |