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Table 3 Logistic regression analyses of seropositivity to P. falciparum-, P. vivax- and Anopheles-specific antigens on Ambae Island. Odd ratios (ORs) and their 95% confidence intervals (95% CI) are presented for both univariate (crude) and multivariate (adjusted) models. Statistical significance was determined using the likelihood ratio test

From: Serological measures to assess the efficacy of malaria control programme on Ambae Island, Vanuatu

  

P. falciparum seropositivity

P. vivax seropositivity

Anopheles seropositivity

Variablea

Category

n/N b

Crude OR

P

Adjusted OR

P

n/N c

Crude OR

P

Adjusted OR

P

n/N

Crude OR

P

Adjusted OR

P

   

(95% CI)

 

(95% CI)

  

(95% CI)

 

(95% CI)

  

(95% CI)

 

(95% CI)

 

Survey year

2003

143/229

1

 

1

 

76/231

1

 

1

 

90/231

1

 

1

 
 

2007

72/280

0.21

(0.14–0.30)

< 0.001

0.19

(0.12– 0.28)

< 0.001

58/275

0.55

(0.37–0.81)

0.003

0.51

(0.33– 0.77)

0.001

2/282

0.01

(0.00– 0.05)

< 0.001

0.01

(0.00– 0.04)

< 0.001

Age group

0–5

19/102

1

 

1

 

20/100

1

 

1

 

15/103

1

 

1

 
 

6–10

51/109

3.84

(2.06– 7.17)

< 0.001

4.07

(2.09– 7.93)

< 0.001

12/107

0.51

(0.23– 1.10)

0.084

0.47

(0.22– 1.04)

0.062

24/108

1.68

(0.82– 3.41)

0.154

1.58

(0.69– 3.63)

0.280

 

11–20

57/111

4.61

(2.48– 8.59)

< 0.001

4.76

(2.45– 9.25)

< 0.001

22/110

1.00 (0.51– 1.97)

1.000

0.93

(0.47–1.84)

0.830

19/111

1.21

(0.58– 2.53)

0.610

0.91

(0.39– 2.09)

0.822

 

> 20

88/187

3.89

(2.18– 6.90)

< 0.001

4.30

(2.32– 7.96)

< 0.001

80/189

2.94

(1.66– 5.18)

< 0.001

2.88

(1.62– 5.13)

< 0.001

34/191

1.27

(0.66– 2.46)

0.478

1.15

(0.54– 2.49)

0.714

  1. a Only variables retained in the final multivariate model are listed
  2. b Four samples were excluded (N = 509); n = number of individuals seropositive to either PfMSP-119 or PfAMA-1, or both
  3. c Seven samples were excluded (N = 506); n = number of individuals seropositive to either PvMSP-119 or PvAMA-1, or both