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Table 2 Sensitivity (S)a and specificity (Sp) of results obtained in Western blot with T24H-his, GST-Ts8B2, GST-T24H, compared to LLGP-EITB test using the collection of serum samples described

From: Comparison of T24H-his, GST-T24H and GST-Ts8B2 recombinant antigens in western blot, ELISA and multiplex bead-based assay for diagnosis of neurocysticercosis

   Sensitivity   
  Specificity (n = 171) One viable cyst (n = 26) Two or more viable cysts (n = 77) Calcified cysts (n = 46)
  (+/−) Sp (%) (+/−) S (%) (+/−) S (%) (+/−) S (%)
T24H-his 1/170 99.4 23/3 88.5 77/0 100 38/8 82.6
GST-Ts8B2 2/169 98.8 19/7 73.1 68/9 88.3 16/30 34.8
GST-T24H 0/171 100 21/5 80.8 74/3 96.1 37/9 80.4
LLGP    22/4 84.6 75/2 97.4 32/11b 74.4
  1. A Chi-square test (χ 2) carried out for each antigen, with degrees of freedom (df) equal to 1 and significance level (P) P < 0.05. T24H-his: χ 2 = 274.488, df = 1, P < 0.001; GST-Ts8B2: χ 2 = 169.289, df = 1, P < 0.001; GST-T24H, χ 2 = 257.855, df = 1, P < 0.001
  2. Abbreviations: n number of sera in each group, +/− number of positive and negative sera obtained in each case, Sp (%) specificity percentage obtained with each antigen in western blot, S (%) sensitivity percentage for each antigen in each NCC group
  3. aSensitivity was determined according to viability and number of cysticerci in neurocysticercosis (NCC) patients
  4. bJust 43 samples from patients with calcified cysts were tested in LLGP-EITB