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Table 2 Sensitivity (S)a and specificity (Sp) of results obtained in Western blot with T24H-his, GST-Ts8B2, GST-T24H, compared to LLGP-EITB test using the collection of serum samples described

From: Comparison of T24H-his, GST-T24H and GST-Ts8B2 recombinant antigens in western blot, ELISA and multiplex bead-based assay for diagnosis of neurocysticercosis

  

Sensitivity

  
 

Specificity (n = 171)

One viable cyst (n = 26)

Two or more viable cysts (n = 77)

Calcified cysts (n = 46)

 

(+/−)

Sp (%)

(+/−)

S (%)

(+/−)

S (%)

(+/−)

S (%)

T24H-his

1/170

99.4

23/3

88.5

77/0

100

38/8

82.6

GST-Ts8B2

2/169

98.8

19/7

73.1

68/9

88.3

16/30

34.8

GST-T24H

0/171

100

21/5

80.8

74/3

96.1

37/9

80.4

LLGP

  

22/4

84.6

75/2

97.4

32/11b

74.4

  1. A Chi-square test (χ 2) carried out for each antigen, with degrees of freedom (df) equal to 1 and significance level (P) P < 0.05. T24H-his: χ 2 = 274.488, df = 1, P < 0.001; GST-Ts8B2: χ 2 = 169.289, df = 1, P < 0.001; GST-T24H, χ 2 = 257.855, df = 1, P < 0.001
  2. Abbreviations: n number of sera in each group, +/− number of positive and negative sera obtained in each case, Sp (%) specificity percentage obtained with each antigen in western blot, S (%) sensitivity percentage for each antigen in each NCC group
  3. aSensitivity was determined according to viability and number of cysticerci in neurocysticercosis (NCC) patients
  4. bJust 43 samples from patients with calcified cysts were tested in LLGP-EITB
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Parasites & Vectors

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