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Table 1 Evaluation of the protective efficacy induced by rSjTOR-ed1

From: Characterization of Schistosoma japonicum tetraspanning orphan receptor and its role in binding to complement C2 and immunoprotection against murine schistosomiasis

Group Worm burden Worm burden reduction in %
(P-value)
EPG EPG reduction in % (P-value)
  Mean ± SD Range   Mean ± SD  
Trial 1
 PBS only (n = 10) 23.30 ± 5.68 17–35    
 PBS + ISA206 (n = 10) 18.55 ± 8.14 9–31   29,384.56 ± 7956.68  
 rSjTOR-ed1 (n = 5) 14.00 ± 2.00 12–16 24.51 (P = 0.054) 17,742.39 ± 9939.94 39.62 (P = 0.0284)
Trial 2
 PBS only (n = 10) 28.00 ± 4.44 16–31    
 PBS + ISA206 (n = 10) 25.40 ± 4.50 19–32   32,848.89 ± 9912.66  
 rSjTOR-ed1 (n = 10) 18.67 ± 4.24 12–25 26.51 (P = 0.002) 22,033.63 ± 7053.50 32.92 (P = 0.0092)