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Table 1 Evaluation of the protective efficacy induced by rSjTOR-ed1

From: Characterization of Schistosoma japonicum tetraspanning orphan receptor and its role in binding to complement C2 and immunoprotection against murine schistosomiasis

Group

Worm burden

Worm burden reduction in %

(P-value)

EPG

EPG reduction in % (P-value)

 

Mean ± SD

Range

 

Mean ± SD

 

Trial 1

 PBS only (n = 10)

23.30 ± 5.68

17–35

   

 PBS + ISA206 (n = 10)

18.55 ± 8.14

9–31

 

29,384.56 ± 7956.68

 

 rSjTOR-ed1 (n = 5)

14.00 ± 2.00

12–16

24.51 (P = 0.054)

17,742.39 ± 9939.94

39.62 (P = 0.0284)

Trial 2

 PBS only (n = 10)

28.00 ± 4.44

16–31

   

 PBS + ISA206 (n = 10)

25.40 ± 4.50

19–32

 

32,848.89 ± 9912.66

 

 rSjTOR-ed1 (n = 10)

18.67 ± 4.24

12–25

26.51 (P = 0.002)

22,033.63 ± 7053.50

32.92 (P = 0.0092)