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Table 1 Interaction of L. donovani ISP1 and ISP2 with trypsin

From: RETRACTED ARTICLE: Role of inhibitors of serine peptidases in protecting Leishmania donovani against the hydrolytic peptidases of sand fly midgut

 

Distance

Donor atom

Acceptor atom

ISP1 and trypsin interacting amino acids

   

 ISP1:PHE103:HN - TRYPSIN:GLY27:O

2.05316

HN

O

 ISP1:TRP135:HE1 - TRYPSIN:SER34:O

2.24518

HE1

O

 ISP1:CYS136:HG - TRYPSIN:GLY208:O

2.20266

HG

O

 ISP1:GLN139:HE22 - TRYPSIN:ILE53:O

2.06784

HE22

O

 TRYPSIN:THR29:HN - ISP1:PHE103:O

1.04559

HN

O

 TRYPSIN:ASN77:HD21 - ISP1:HIS56:NE2

1.9625

HD21

NE2

 TRYPSIN:ASN77:HD22 - ISP1:HIS56:NE2

2.34771

HD22

NE2

 TRYPSIN:VAL152:HN - ISP1:HIS96:NE2

2.4941

HN

NE2

ISP2 and trypsin interacting amino acids

   

 ISP2:ARG65:HH22 - Trypsin:HIS91:O

2.26049

HH22

O

 ISP2:THR74:HN - Trypsin:THR149:OG1

2.17454

HN

OG1

 ISP2:THR113:HN - Trypsin:SER96:O

2.39979

HN

O

 ISP2:ASN114:HD21 - Trypsin:HIS57:NE2

1.13056

HD21

NE2

 ISP2:ASN114:HD22 - Trypsin:HIS57:NE2

2.43346

HD22

NE2

 ISP2:LEU116:HN - Trypsin:GLY216:O

1.79443

HN

O

 Trypsin:TYR94:HH - ISP2:SER112:OG

2.15161

HH

OG