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Fig. 1 | Parasites & Vectors

Fig. 1

From: Interaction of primary mast cells with Borrelia burgdorferi (sensu stricto): role in transmission and dissemination in C57BL/6 mice

Fig. 1

Mouse mast cell response to Borrelia and OspC. Primary MCs from C57BL/6 mice were activated with different concentrations of Borrelia burgdorferi (s.s.) 297 strain (MOI 10:1 or 50:1) or Lipidated-OspC (L-OspC: 10 or 50 ng/ml). After 2 h, the level of degranulation was evaluated by measuring β-hexasominidase release and percentage degranulation was calculated according to the negative control (a). After 24 h, supernatants were collected to measure IL-6 concentration by ELISA (b). After 6 h, RNAs were collected to measure IL-6 and MCP-1 mRNA expression (c, d). *P < 0.05; ***P < 0.001

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