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Fig. 2 | Parasites & Vectors

Fig. 2

From: Interaction of primary mast cells with Borrelia burgdorferi (sensu stricto): role in transmission and dissemination in C57BL/6 mice

Fig. 2

Mouse mast cell response to Borrelia OspC-KO. Primary MCs from C57BL/6 mice were activated with medium (Ø) Borrelia burgdorferi (s.s.) (Bb) 297 (Wt), Bb OspC-KO (OspC-KO) or Bb OspC-complemented strains (OspC-Compl.) (MOI 50:1). After 24 h, supernatants were collected to measure IL-6 concentration by ELISA (a). After 6 h RNAs were collected to measure IL-6 and MCP-1 mRNA expression (b, c). *P < 0.05; **P < 0.01; ***P < 0.001

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