Skip to main content
Fig. 2 | Parasites & Vectors

Fig. 2

From: Screening of the ‘Stasis Box’ identifies two kinase inhibitors under pharmaceutical development with activity against Haemonchus contortus

Fig. 2

Dose-response curves for compounds SNS-032 (MMV690767) and AG-1295 (MMV079840) on larval stages of Haemonchus contortus in vitro with reference to the positive-control compound monepantel. Inhibition of motility of (a) third-stage (xL3) and (b) fourth-stage (L4) larvae at 72 h and of development of fourth-stage larvae (L4s) at 7 days (c) of exposure to each of the compound. Assessment of the toxicity of compounds SNS-032 (MMV690767) and AG-1295 (MMV079840) on breast epithelial (MCF10A) cells after 48 h of exposure to each compound in vitro (d). Each data point represents the mean of two to five experiments repeated in triplicate on different days (± standard error of the mean, SEM)

Back to article page

Parasites & Vectors

ISSN: 1756-3305

Contact us