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Fig. 3 | Parasites & Vectors

Fig. 3

From: Absence of Batf3 results in reduced liver pathology in mice infected with Schistosoma japonicum

Fig. 3

Immune responses of Batf3 −/− and B6 mice after S. japonicum infection. Th1, Th2, Tc1, and Tc2 immune response were detected by FCM at 0, 3, 6 and 9 weeks post-infection of each group. Tc1 cell responses are stronger in S. japonicum infected Batf3 −/− mice, Th1, Th2, and Tc2 cell responses show no significant difference between Batf3 −/− and WT B6 mice after S. japonicum infection. a, b Percentages of CD3+CD4+IFN-γ+ (Th1) gated from CD3 + T cells analysed by FCM. c, d Percentages of CD3+CD4+IL-4+ (Th2) gated from CD3 + T cells analysed by FCM. e, f Percentages of CD3+CD8+IFN-γ+ (Tc1) gated from CD3 + T cells analysed by FCM. g, h Percentages of CD3+CD8+IL-4+ (Tc2) gated from CD3+T cells analysed by FCM. Results are representative of two independent experiments. Each bar represents the mean ± SEM from six mice per group. (*P < 0.05, **P < 0.01)

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