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Fig. 4 | Parasites & Vectors

Fig. 4

From: Absence of Batf3 results in reduced liver pathology in mice infected with Schistosoma japonicum

Fig. 4

Tc1 cell responses induced by Batf3-independent CD8α+ DCs. a A small amount of CD8α+ DCs was detected in the Batf3 −/− mouse schistosomiasis infection model.Percentages of CD11c+CD8a+cells analysed by FCM at 9 weeks post-infection. The upper right quadrant is the proportion of CD8α+ DCs cell subsets. b Expression of Irf8, PU.1, Id2, Nfil3 and Batf3genes of Batf3 −/− and B6 mice after S. japonicum infection. Expression of Irf8, PU.1, Id2, Nfil3 and Batf3 genes in the spleen were detected at 0, 3, 6 and 9 weeks post-infection by RT-PCR. (**P < 0.01, ***P < 0.001) Results are representative of two independent experiments. Data are presented as the mean ± SEM from six mice in each group

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