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Table 2 Ex vivo and in vitro susceptibility of Plasmodium falciparum isolates to chloroquine

From: Return of chloroquine sensitivity to Africa? Surveillance of African Plasmodium falciparum chloroquine resistance through malaria imported to China

Isolate

IC50 (nM)

Ex vivo

In vitro

1

113

151.7

2

15.9

9.7

3

11.3

11.9

4

4.8

11.9

5

10.5

25

6

32.3

31.3

7

60.3

43.3

8

57.6

56.8

9

20.4

133

10

23.8

6.1

  1. Note: Total ten P. falciparum isolates were tested for their sensitivity to chloroquine with paired fresh and culture-adapted samples, and the correlations and differences between IC50 values were tested, with Spearman’s correlation coefficient of 0.679 (P = 0.31), and there was no significant difference in mean IC50s between them (Z = -0.357, P = 0.720)
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Parasites & Vectors

ISSN: 1756-3305

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