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Fig. 4 | Parasites & Vectors

Fig. 4

From: The N- and C-terminal carbohydrate recognition domains of Haemonchus contortus galectin bind to distinct receptors of goat PBMC and contribute differently to its immunomodulatory functions in host-parasite interactions

Fig. 4

rMCh was much more potent than rMNh in inhibiting cell proliferation. PBMC were activated with ConA and incubated at the same time with 40 μg/ml recombinant proteins or recombinant empty protein pET32a (control) at 37 °C and 5% CO2. The proliferation was measured by CCK-8 incorporation after 72 h. Cell proliferation index was calculated considering the OD450 values in blank group as 100%. PBMC used for all replicates of distinct treatments in each experimental repetition were derived from the same goat. Results presented here are representative of three independent experiments. Data are presented as the mean ± SD, *P < 0.01, **P < 0.001 vs the control group, a capped line designates two groups that differ significantly (*P < 0.01, **P < 0.001)

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