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Table 1 Performance of each antigen in ELISA when including all three groups of dog sera. True positive sera (n = 14 of group 1) were analysed together with true negative sera (group 3) plus the selected sera from the serobank (group 2). This scenario yields a realistic impression of routine analysis of dogs for AE in Switzerland

From: Dogs as victims of their own worms: Serodiagnosis of canine alveolar echinococcosis

ELISA AUC Cut-off Sensitivity (95% CI) Specificity (95% CI)
recEm95 1 0.261 1 (0.72–1) 1 (0.93–1)
Em2 0.837 0.430 0.79 (0.52–0.92) 0.97 (0.89–0.99)
EmVF 0.967 0.574 1 (0.78–1) 0.85 (0.74–0.92)
recEm18 0.838 0.329 0.79 (0.52–0.92) 0.85 (0.74–0.92)
  1. Abbreviations: AUC area under curve, CI confidence interval