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Table 1 Performance of each antigen in ELISA when including all three groups of dog sera. True positive sera (n = 14 of group 1) were analysed together with true negative sera (group 3) plus the selected sera from the serobank (group 2). This scenario yields a realistic impression of routine analysis of dogs for AE in Switzerland

From: Dogs as victims of their own worms: Serodiagnosis of canine alveolar echinococcosis

ELISA

AUC

Cut-off

Sensitivity (95% CI)

Specificity (95% CI)

recEm95

1

0.261

1 (0.72–1)

1 (0.93–1)

Em2

0.837

0.430

0.79 (0.52–0.92)

0.97 (0.89–0.99)

EmVF

0.967

0.574

1 (0.78–1)

0.85 (0.74–0.92)

recEm18

0.838

0.329

0.79 (0.52–0.92)

0.85 (0.74–0.92)

  1. Abbreviations: AUC area under curve, CI confidence interval